Periventricular White Matter Hyperintensities and Functional Decline
نویسندگان
چکیده
منابع مشابه
Should we distinguish between periventricular and deep white matter hyperintensities?
Periventricular and Deep White Matter Hyperintensities? To the Editor: The recent article by DeCarli et al1 addresses a somewhat neglected aspect of white matter hyperintensities (WMH), the significance of their anatomical location. The authors argue that the commonly accepted categorization into deep (DWMH) and periventricular (PVWMH) WMH is arbitrary, because the 2 are very highly correlated,...
متن کاملPeriventricular cerebral white matter lesions predict rate of cognitive decline.
The prospect of declining cognitive functions is a major fear for many elderly persons. Cerebral white matter lesions, as commonly found with magnetic resonance imaging, have been associated with cognitive dysfunction in cross-sectional studies. Only a few longitudinal studies using small cohorts confirmed these findings. We examined the relation between severity of white matter lesions and cog...
متن کاملWhite matter hyperintensities predict functional decline in voiding, mobility, and cognition in older adults.
OBJECTIVES To compare magnetic resonance imaging data with functional assessments of mobility, urinary control, and cognition to determine common or distinctive features in the distribution of brain white matter hyperintensities (WMHs) associated with functional decline and impairment. DESIGN Baseline data from subjects aged 75 to 89 enrolled in a longitudinal study. Assessors and subjects we...
متن کاملIncrease in periventricular white matter hyperintensities parallels decline in mental processing speed in a non-demented elderly population.
OBJECTIVE To investigate the influence of deep white matter hyperintensities (DWMH) and periventricular white matter hyperintensities (PVWMH) on progression of cognitive decline in non-demented elderly people. METHODS All data come from the nested MRI sub-study of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). We performed a 3 year follow up study on 554 subjects of th...
متن کاملCortical Thinning Mediates the Correlation between Periventricular White Matter Hyperintensities and Cognitive Impairments
Introduction: Previous studies showed that white matter lesions (WMLs) were an important risk factor for cognitive impairment, but the mechanisms whereby WMLs induced cognitive impairment have not been clarified. We hypothesised that the correlation between WMLs and cognitive impairments would be mediated by cortical thinning. Methods: Patients with periventricular white matter hyperintensities...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Geriatrics Society
سال: 2017
ISSN: 0002-8614,1532-5415
DOI: 10.1111/jgs.15149